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Scientist Print Cells On To Wounded Flesh

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Scientist Print Cells On To Wounded Flesh

Printing directly cells onto wounds could reduce healing time by more than 50 percent…

Scientists from the Wake Forest’s Institute for Regenerative Medicine have developed a ink-jet style bioprinter that can print healthy human cells directly onto wounded flesh to promote healing and considerably shorten recovery time.

During initial tests on mice, the device was found to heal wounds within two weeks, a process that usually takes up to 5 weeks. Kyle Binder, a student on the team who helped design the device said:

We literally print the cells directly onto the wound. We can put specific cells where they need to go…

We were able to close the entire wound in two weeks.

bioprint humans cells onto wounded flesh 550x366 Scientist Print Cells On To Wounded Flesh

Cell Fabrication With InkJet-Style Printer

To administer healthy cells onto wounded flesh, Binder and the team first dissolved cells from human skin, separating and purifying various cell types such as fibroblasts and keratinocytes. The cells are then cultured in a nutritious solution to make them multiply.

A machine similar to an office inkjet printer applies a layer of fibroblasts, followed by a layer of keratinocytes which form the protective outer layer. The device is mounted on a frame that can be easily wheeled in position over a hospital bed.

The sprayed cells incorporated themselves into surrounding skin, hair follicles and sebaceous glands. This is probably due to the stem cell content of the mixture, the researchers said. Binder added:

“You have to give a lot of credit to the cells. When you put them into the wound, they know what to do,

The team is working closely with the U.S. Armed Forces Institute of Regenerative Medicine to come up with new ways of treating wounded soldiers in Iraq and Afghanistan. And the new device could be just the solution.

Experts say that victims suffering from server burns often die of infection within two weeks unless they receive skin grafts and conventional skin grafts leaves scars. Bioprinting cuts down healing period sufficiently to reduce the amount of deaths caused by infection.

The next phase involves testing bioprinting on pigs and eventually the team will seek U.S. Food and Drug Administration approval to test the device on humans.


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